Herbal medicine has been a common treatment modality
for hundreds of years and in many instances, herbs have shown dramatic ability to reduce inflammatory mediators naturally. The proprietary formula Cur-OST® was evaluated in a clinical trial in 2006 evaluating the impact on horses with clinical arthritis. In that study, Cur-OST® demonstrated an ability to reduce synovial fluid levels of inflammatory mediators PGE-2 and MMP-9. Given the success with that small trial and considering the possible link between inflammation and insulin resistance demonstrated in human literature, Cur-OST® was evaluated in horses demonstrated to have suspected insulin resistance and clinical laminitis.